SyNAPSE is not a project DARPA undertook lightly. Many attempts at large-scale neuromorphic engineering have been made in the past. None met their goals. As such, SyNAPSE owes its existence to a number of recent game-changing developments. From HP Labs, the discovery of the memristor was one such keystone innovation. It took Greg Snider’s 2007 work in Nanotechnology, however, to establish memristors as a viable platform for the implementation of self-organizing recurrent neural networks.